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Human Evolution & Genetics: Cultural Approaches to Selection & Heredity - Prof. G. Listi, Study notes of Introduction to Cultural Anthropology

An overview of human evolution and genetics, covering topics such as holistic and comparative approaches, the history of evolutionary thought, natural selection, heredity, and mendelian genetics. It includes key figures like charles darwin, james hutton, and gregor mendel, and discusses concepts such as adaptation, genetic drift, and balanced polymorphism.

Typology: Study notes

2011/2012

Uploaded on 09/17/2012

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Download Human Evolution & Genetics: Cultural Approaches to Selection & Heredity - Prof. G. Listi and more Study notes Introduction to Cultural Anthropology in PDF only on Docsity! Unit 1 Anthropology- study of man. Perspectives of Anthropology: -Biocultural Approach-helps to understand people; relationship between what humans have inherited genetically and what they learn culturally.  Humans are product of both genes and cultural approach.  -Holistic: Concerned with a whole system(includes everything about humans: behavior, how eat, reproduction, body structure)  -Comparative(Cross-culture): make comparisons to draw meaning  if different, why different  -Ethnocentric: view centered on a specific ethnic group(Usually one’s own ethnic group).  Belief in the inherent superiority of one’s own ethnic group or culture.  Ex: Yononami(“the humans”): indigenous people in South America  -Cultural “Relativism”: view that considers human interactions and behavior within their own cultural context. Keeping an open mind about a particular group or culture.  Ex: most common form of marriage in the world today- Polygamy-One man married to multiple women  Ex: Na: an indigenous group in China, men go around having “relations” with women. Child views mother’s brother as father figure.  Ex: Efik: Culture in Africa like the women fat; go to fattening room before marriage.  -Fieldwork(data collection): going out into the “field” and studying a culture, spending time in a museum, excavation at a site , analyzing in a lab.   Four Subfields :  1. Linguistic Anthropology- focuses on language/communication. Study social norms of communication within a culture, origin of language, gender speech variation.  2. Cultural Anthropology(Sociocultural)- Learned behavior, distinct among groups; passed down through generations; changes; 5,000 distinct diff cultural groups. (Culture)  3. Archaeology- Studying past human behavior based on the material remains of what they left behind. Two types: academic (study and learn about archaeology) and contract (jobs in archaeology. Have firms like law firms).  4. Biological Anthropology- (aka physical anthropology) biological aspects of humans (race), study of close relatives (primates), fossil records. Study of human biological evolution and human bio-cultural variation.  American Anthropology  -Fronz Boas: set standard for American anthropology- “Father”  “4-field” approach, Biocultural perspective (Wholism), trained 1st generation. -Ales Hrdlieka: started the American Journal of Physical Anthropology  organized scientific society of- American Association of Physical Anthropologists   History of Evolutionary Thought  Charles Darwin : Biological Sciences; published Origin of Species  Idea of Evolution (species change)  Adaptive Radiation : from a single ancestor (species) you can have multiple descendants (species); one common ancestor.  Gradualism: a gradual (slow) change; evolution  Natural Selection : ”Survival of the fittest”. Impact of the environment on living forms.  Middle Ages:  order – Idea that everything can be arranged heiarchaly. There is a natural arrangement of life.  stasis – idea of consistency (things don’t change)  heavily influenced by religious beliefs – “great chain of being”   Examples of Natural Selection  Medium ground Finches o The birds with the larger and tougher beaks survived because of the food source change during a drought.  Peppered Moth o Black colored moth became more common than white during the industrial revolution – predators could see white moths more easily  Antibiotic Resistance o Ex) multidrug-resistant tuberculosis (MDR TB) Methicillin – resistant staph (MRSA)   Heredity  Homunculus – “little man,” in every sperm cell there was a little person that just got bigger  Blending inheritance – Each parent contributes tiny particles that represent different body parts that blend and develop into a human  Cells o prokaryotic – simple life forms. No nucleus. o eukaryotic – nucleus; organelles.  cell types o somatic cells – body, muscles, bones. Body cells. o gametes – sex cells, reproduction  DNA  2 chains of nucleotides (sugar + phosphate + nitrogenous base)  bases (A, G, C, T)  base – pair specificity – bases bind in very specific pattern with each other  replication (growth, development, maintenance, repair) o DNA’s ability to copy itself  Nuclear DNA (nDNA) o Nucleus of every cell (except rbc), 1000’s of genes, “blueprint” template for protein production, homoplasmic (same in every cell)  Mitochondrial DNA (mtDNA) o found in mitochondria o 37 genes (much smaller section of DNA) o assist with mitochondria functions (ATP) o heteroplasimic- not identical in every cell Heredity  gene – sequence of DNA, responsible for cell function o structural – coding for different kinds of proteins, responsible for body structures o regulatory  regulates the expression of other genes (turns genes on and off)  Homeotic (hox) genes – how the body forms tissues and organs. Guides embryological development.  Chromosome – sequence of genes (46 total) Karyotype= layout of an individuals’ different chromosomes. o 23 homologous pairs – chromosomes that carry the same genetic information, code for the same traits, same size, but not identical to each other o autosomes (22 pairs/44 individuals) – carry info of the body (physical characteristics, except for primary sexual characteristics) o sex chromosomes (1 pair/ 2 individuals) – determine the sex of the individual   Cell Division Comparison  Mitosis : Division of Somatic cells  2 daughter cells  identical to each other and the original  diploid  occurs for growth and development, tissue repair, body maintenance  Meiosis : Cell division that produces Gametes  Recombination (crossing over) occurs – the exchange of genetic material between homologous chromosomes during meiosis; creates variation  4 daughter cells  not identical to each other or the original  haploid (half the compliment of DNA=23)  gamete development   Cell Division Mistakes  -Nondisjunction: failure of chromosomes to separate during meiosis, more serious if it happens in autosomes  Sickle cell anemia.  Tay-Sachs, Cystic Fibrosis- both fatal  “Carriers”- if only have one carrier of the allele, passes it on  heterozygote expression- impacts body, carriers have some impact  II. Polygenic Inheritance -“Polygenic traits”- traits coded for genes at more than one locus  Continuous in expression (show a range of expression)  Ex: sin color, eye color, face shape  Melanin production- darkness of skin color  Multiple loci contribute  Codominant alleles   Environmental Influence: environmental influences polygenic inheritance. Ex. height  Pleiotropy : 1 Gene that can influence many traits   Modern Theory of Evolution  Evolution : The change in the genetic frequencies in a trait in a population over time  Production and distribution of genetic variation  Natural Selection  Microevolution : Small scale adaptive changes in a population  Macroevolution : Large scale changes that have resulted in a specific speciation event  Deme (population) : Group of organisms that interbreed regularly and produce offspring.  Gene Pool : entire genetic information of a population  Hardy-Weinberg Equilibrium : Mathematical equation that predicts allele distribution in a population under ideal conditions.   Influence of Allele Frequency  1. Mutation: Change in the DNA sequence; only way for new combination of alleles/ DNA to occur  2. Gene Flow: Movement of alleles between populations  3. Genetic Drift: random change in allele frequencies  Bottle Neck Effect : start out with large genetically diverse population that is suddenly and drastically reduced; variation is lost for future generations  Founder Effect : start out with small population; small group of individuals set out and colonize an area o Ex: Ellis-Van Creveld Syndrome: affects dwarfism and polydactylism; more frequent in Amish population. Recessive allele affects autosomes  4. Natural Selection: Differential reproductive success under specific environmental circumstances  Influences on allele frequencies  Balanced Polymorphism (Heterozygote advantage): Maintenance of 2 or more alleles in a population due to the selective advantage of the heterozygote o Sickle cell allele- strongest in dark areas, recessive allele, must receive 2 copies (homozygotes), alters the shape of blood cells, usually located around another disease Malaria (spread by parasite)-carriers of sickle cell are better prepared or malaria. o Other (Possible) Balanced Polymorphism: o –Tay-Sachs (Ashkenazim)- need two copies of recessive allele, impacts neurological system, and shows signs by 6 months, death by 2-3 years. May gives an advantage against the bacteria that causes tuberculosis. o –Cystic Fibrosis- causes a lot of problems for your digestive tract, but helps against cholera (causes loss of nutrients and dehydration). Human Variation  Hypertension in African Americans: African Americans have higher blood pressure o Founder effect + Natural Selection, High salt retention  Genetic, weight, salt excretion, stress  Research has shown that best response comes from effecting that salt intake-(medicine, diet)   Human Variation  -“Voyages of Discovery”- 1500s-1700s  Monogenism : all humans descended from a single original pair (Adam & Eve), any variation is due to environmental variation  Polygenism : different populations were descendants of different pairs of ancestors  -Early studies (18th-early 19th centuries)  descriptive/classifying different populations of humans  -Mid 19th century:  Biological Determination : the idea that behavioral attributes are associated with biological attribute (intelligence, behavioral morals) Race Common definitions: -species -cultural/ethnic identity -religious identity -physical characteristics - has come to have a negative connotation. “Ethnicity” , “Ancestry” are substitute words for race (which has had negative meanings toward physical differences between races).
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