Renal Physiology and Electrophysiology Hw #1, Assignments of Biology

Download Renal Physiology and Electrophysiology Hw #1 and more Assignments Biology in PDF only on Docsity! MED. SCI. III Hw #1 Spring 04 1) Compute the equilibrium potentials for K+ and Ca++ using the Nernst equation. 2) It has been said that the Earth’s atmosphere is analogous to a cell membrane. Explain this statement by considering the functions required of a cell membrane and their analogy in the atmosphere. 3) Use the data provided to answer Questions 1-7 Urine Flow Rate 1 ml/minute Plasma Concentration of Inulin 100 mg/ml Urine Concentration of Inulin 12 g/ml Renal Arterial Concentration of PAH* 1.2 mg/ml Renal Vein Concentration of PAH 0.1 mg/ml Urine Concentration of PAH 650 mg/ml Plasma Concentration of Substance A 10 mg/ml Urine Concentration of A 2 g/ml Plasma Concentration of B 10 mg/ml Urine Concentration of B 10 mg/ml Hematocrit 0.45  PAH stands for para-aminohippuric acid, a substance used to measure renal blood flow. Its properties differ from inulin in that PAH is both filtered and secreted in nephrons whereas inulin is only filtered. The equation for measuring the ‘true’ renal plasma flow with PAH is based upon the Fick principle of conservation of mass. The Fick principle states that the amount of PAH entering the kidney through the renal artery equals the amount leaving the kidney through the renal vein and ureter. Note that the relationship between plasma flow and blood flow is given by the flowing equation: RBF = RPF/(1-Hct) Where RBF = renal blood flow; RPF = renal plasma flow; and Hct = Hemotocrit (the fraction of blood volume occupied by cells). Use the data above, your knowledge of kidney function from lecture and texts to answer the following questions. You may make reasonable assumptions so long as those assumptions are identified. a What is the value for the glomerular filtration rate (GFR)?