Acute Kidney Injury related notes, Study notes of Nephrology

Download Acute Kidney Injury related notes and more Study notes Nephrology in PDF only on Docsity! AKI: - Normal Urea and Creatinine - BUN/Cr and Urea/Cr ratios Note: Causes of abnormal Urea/Cr ratio: INCREASED UREA:CREATININE RATIO – (Drivers Can use GPS)  dehydration/prerenal failure  corticosteroids  GI haemorrhage  protein-rich diet  severe catabolic state DECREASED UREA:CREATININE RATIO (I am a SIMPLE SR)  severe liver dysfunction  intrinsic renal damage  malnutrition  pregnancy  low protein diet  SIADH  Rhabdomyolysis - Causes of AKI: - Drugs that cause AKI: -Criteria of AKI: RIFLE Criteria AKIN Criteria Cr/GFR criteria + UO criteria Cr criteria + UO criteria 5 stages 3 stages NOTE: If pt requires RRT then pt is stage 3 NOTE: Markers of AKI can increase without renal failure: - Cr 1- drugs: amiloride,trimethoprim, cefoxitin ,cimetidine , flucytosine. 2- ketoacidosis 3- Rhabdomyolosis/MG -Blood urea 1- gastrointestinal bleeding. 2- excessive protein intake. 3- decreased urinary flow. 4- tissue trauma. 5- drugs: glucocorticoids, tetracycline. -Urinary Indices: ATN Pre-renal Index <350 >500 U. Osmolality (mOsm/kgwater) >40 <20 U.Na (meq/l) <20 >40 U/P Creatinine >1 <1 FENa