Fundamentals of Pharmacology: Definitions and Concepts, Exams of Pharmacology

Download Fundamentals of Pharmacology: Definitions and Concepts and more Exams Pharmacology in PDF only on Docsity! basic concepts of pharmacology define DRUG - any chemical that affects life processes define clinical pharmacology - study of drugs in humans pharmacotherapeutics - the use of drugs to diagnose, prevent, treat, or manage disease or prevent pregnancy define prototype - first drug developed to treat a condition define pharmacokinetics - drug motion, explains what the body does to the drug what are the four processes involved in pharmacokinetics - absorption, distribution, metabolism, excretion define absorption - drug into blood stream define distribution - drug from blood to interstitial space of tissues then into cells define metabolism - biotransformation of drug structures define excretion - mvmt of drug out of the body how do drugs produce their effects - by interacting with receptors what types of drugs do not involve receptors - antacids, antiseptics, laxatives, chelating agents define interpatient variability - dose of med necessary to produce a response varies from patient to patient define ED50 - midpoint of the frequency distribution of effective doses dose required to produce a therapeutic response therapeutic index - measure of drug safety ratio of LD50 to ED50 what determines a not safe drug - a low therapeutic index define additive - two drugs with similar pharmacologic actions are taken define synergistic - one drug enhances the effect of another