capillary viscometer equation, Cheat Sheet of Chemistry

Download capillary viscometer equation and more Cheat Sheet Chemistry in PDF only on Docsity! Lecture -4 Pharmaceutical Compounding I PHR3325C Quality Control test for Syrup& Elixirs Presented By:Dr Amit Sharma Assistant Professor of the Pharmacy Department, Kom a r U n iv e r s it y o f S c ie n c e a n d T e c h n o logy Topic:- Quality Control tests for Syrups And Elixirs. 2) Light Transmittance Meter:- © A light transmittance meter is a newer tool that is used to check syrup color. In a light transmittance meter, a syrup sample is checked for color by passing light through the sample. The percent of light transmission is compared to light transmission rates set for different grades. When using one, you need to be sure there are no fingerprints on the syrup test bottle, and that the syrup sample has no bubbles or cloudiness. Any of these conditions may diminish the light that is transmitted through the sample and therefore lowers the grade of the sample. 3) Visual Inspection:- © With visual inspection, the ingredients and the final products are carefully examined for purity and for appearance. © Physical appearance of products for patient adherence and compliance is critical so it should be ¥ Good looking ¥ Elegance in appearance 4) pH Measurement:- © The measurement and maintenance PH is also very important step in the Quality control testing. © Generally there are 2 different types of methods used in the measurement of pH. 6) Sucrose concentration:- © The determination of Sucrose concentrations is also very important in Quality control testing of syrups. if the concentration Sucrose in the syrup is very high it may crystallize the syrup and less sucrose concentrations give favor for the microbial growth. There is no specific method for the determination sucrose in syrup, we use Hplc and uv-spectroscopy for this purpose.  1) Determination of alcohol conc. Elixir usually contains 5 to 40% alcohol. The determination of alcohol unless otherwise specified in the individual monograph. It is suitable for examining most fluidextracts and tinctures and elixirs provided the capacity of the distilling flask is sufficient (commonly two to four times the volume of the liquid to be heated) and the rate of distillation is such that clear distillates are produced. Cloudy distillates may be clarified by agitation with talc, or with calcium carbonate. And filtration is done. After which the temperature of the filtrate is adjusted and the alcohol content determined from the specific gravity. During all manipulations, take precautions to minimize the loss of alcohol by evaporation. For Liquids it is Presumed to Contain.Jess than 30% of Alcohol. >Dynamic Viscosity: The resistance to flow encountered when one layer or plane of fluid attempts to move over another identical layer or plane of fluid at a given speed. Dynamic viscosity is also called absolute viscosity. > Kinametic viscosity: Addition and deletion of force is known as the kinematic viscosity. Methods used for Measurement of Viscosity Method 1 (U tube viscometer) 4) Concentric cylinder viscometers also known as absolute viscometers. 5) Cone-plate viscometers 6) Spindle viscometers (relative vi meters