Classification of Amino Acids - Biochemistry - Lecture Slides, Slides of Biochemistry

Download Classification of Amino Acids - Biochemistry - Lecture Slides and more Slides Biochemistry in PDF only on Docsity! Citrate -Ketoglutarate Succinyl CoA Fumarate Oxaloacetate Pyruvate Acetyl CoA Acetoacetyl CoA Alanine Glycine Cysteine Serine Threonine Tryptophan Isoleucine Leucine Tryptophan Glutamate Glutamine Histidine Proline Arginine Leucine Lysine Phenylalanine Tyrosine Tryptophan Isoleucine Methionine Valine Aspartate Asparagine Tyrosine Phenylalanine Aspartate Docsity.com Classification of Amino Acids • Amino acids that can form gluconeogenic precursors are called “glucogenic” (pyruvate, -ketoglutarate, succinyl-CoA, fumarate, or OAA) • Amino acids that form acetyl-CoA or acetoacetate are called “ketogenic” • Many are BOTH Docsity.com CH2C-COO - H NH3 HO CH2 C-COO - O HO P. 637 Homogentisate CH2-COO - HO OH H O COO- C=C O=C CH2 CH2-COO - C H C=C H O COO- O=C CH2 CH2-COO - C H Fumarate + acetoacetate Fumarylacetoacetate Maleylacetoacetate Oxidized Homogentisate oxidase Alcaptonuria O2 L-Tyrosine Tyrosine amino transferase Docsity.com Methionine Homocysteine P 630 SH CH2 CH2 H3N-CH-COO - OH CH2 H3N-CH-COO - S CH2 CH2 H3N-CH COO- CH2 CH COO- NH3 + Cystathione -lyase CH3 CH2 C=O COO- CH2-SH CH COO- NH3 + +  -Ketobutyrate Cysteine Cysteine is made from Methionine and Methionine goes to Succinyl CoA -H2O Cystathionine Serine NH4 + Propionyl CoA Succinyl CoA Docsity.com CH3-C-COO - +NH3 H Alanine Cysteine HS-CH2C-COO - O CH3C-COO - O -Kg Glutamate Pyruvate SO4 2- Sulfate [S] -Mercaptopyruvate H2S 2RSH HS-CH2-C-COO - +NH3 H O2S-CH2-C-COO - +NH3 H = Taurine CO2 O2 Serine -H2O -NH4 Glycine O3S-CH2-CH2-NH3 + = p625 -NH4 + Sulfinic acid Docsity.com