Download Leishmaniasis, Sleeping Sickness, and Parasitic Infections: Definitions and Stages and more Quizzes Biology in PDF only on Docsity! TERM 1 Old World Cutaneous Leishmaniasis DEFINITION 1 Leishmania Tropica Complex concave lesion TERM 2 New World Cutaneous Leishmaniasis DEFINITION 2 Leishmania mexicana complex dry, scabby lesion TERM 3 Mucocutaneous Leishmania DEFINITION 3 Leishmania braziliensis complexamastigotes spread from original bite into mucous membranes and erode soft tissues and palate TERM 4 Visceral Leishania DEFINITION 4 Leishmania donovani complexamastigotes spread from bite into visceral orans and replicate in great numbers. Fatal within 2 years if not treated TERM 5 West African Sleeping Sickness DEFINITION 5 T. brucei gambiense - tsetse fly vector Disease Stages Asymptomatic incubation period : weeks, chancre on skin at site of infection. Spread of organism throughout lymphatics: fever, malaise, anorexia, night sweats, swollen lymph nodes Meningoencephalitis: fatigue, mental dullness, excessive sleepiness, emaciation, coma, death TERM 6 East African Sleeping Sickness DEFINITION 6 T. brucei rhodesiense - tsetse fly vectorDisease Stages - More Asymptomatic incubation period : weeks, chancre on skin at site of infection. Spread of organism throughout lymphatics: fever, malaise, anorexia, night sweats, swollen lymph nodes Meningoencephalitis: fatigue, mental dullness, excessive sleepiness, emaciation, coma, death TERM 7 Chagas' Disease DEFINITION 7 T. cruzi - Reduviig (kissing) bug vector replication of amastigotes in heart, brain, and viscera Children under 5 years old usually Acute local inflammation at bite site as organism migrates to lymph nodes Lymphatic draining blocked causing painful lesion Fever, chills, malaise, myalgia, fatigue Cardiomyopathy and CNS symptoms, sometimes death TERM 8 T. Rangeli DEFINITION 8 Self-limiting asymptomatic infectionCan be used to make vaccination for T. cruzi <- fun fact. TERM 9 Cryptosporidium parvum Life cycle DEFINITION 9 Sporozoites felease from oocyst in GI tract of humans - invasion of epithelial cells Schizogony within epithelial cells to produce schizonts w/ merozoites Schizonts undergo sporogony to produce micro and macro gametes Macro and micro gametes unite to form zygote which matures into an oocyst Thick walled released into environmen thin walled oocysts auto-infect TERM 10 Cryptosporidium parvum DEFINITION 10 Pathogenesis Self limiting watery diarrhea with nausea, fever, vomiting, ab cramps in immunocopetent severe intractable diarrhea with no treatment response in immunocompromised Diagnosis Oocysts stain with modified acid fast stain oocysts are 4-6 um (if bigger than 7 is not cryptosporidium) EIA
