Neonatal Reproductive Systems: Testis, Spermatogenesis & Follicle Growth - Prof. Douglas N, Study notes of Biology

Download Neonatal Reproductive Systems: Testis, Spermatogenesis & Follicle Growth - Prof. Douglas N and more Study notes Biology in PDF only on Docsity! 10 April Neonatal Testis Testicular cords contain gonocytes and Sertoli cells Interstitium contains Leydig cells, blood vessels Testicular cords in neonatal → seminiferous tubules in adult Tunica propria – basement membrane Sertoli Cells Form tight junctions – blood testis barrier Support germ cells – physically, nutrition Secrete fluids Secrete inhibin – feedback to brain Phagocytose defective sperm Secrete androgen binding protein In fetal life, secrete AMH (anti Mullerian hormone) Spermatogenesis Make lots of sperm – spermatocytogenesis Make haploid sperm – meiosis Metamorphosis – spermiogenesis Spermiogenesis: spermatid → spermatozoa Head Acrosome and nucleus Midpiece Centrioles and mitochondria Tail (flagellum) Microtubules Regulation of Spermatogenesis Testosterone Stimulates spermatogenesis Maintain Wolffian duct, accessory glands External genitalia, secondary sex characteristics Stimulate metabolism (muscle growth) Affect CNS function/behavior Anabolic Steroids and Testicular Morphology Testosterone is an anabolic (growth- and storage- promoting) steroid Destroys testis through negative feedback Efferent ducts absorb fluid Sperm Transport: Epididymis Head, body, and tail region Storage, fluid reabsorption Acquire motility