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Mechanism of Action and Treatment of Substance Use Disorders and Intoxication, Exams of Nursing

An in-depth examination of various substances, their mechanisms of action, and the treatments for substance use disorders and intoxication. Topics covered include opioids, cocaine, alcohol, and medications used for smoking cessation, dementia, depression, adhd, and sexual dysfunction. The document also discusses the treatment of co-occurring disorders and the importance of monitoring side effects.

Typology: Exams

2023/2024

Available from 05/15/2024

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Download Mechanism of Action and Treatment of Substance Use Disorders and Intoxication and more Exams Nursing in PDF only on Docsity! NSG 552 EXAM 3 -with 100% verified solutions 2024 Tutor verified What is the mechanism of action of Naloxone? Pure opioid antagonist that competes and displaces opioids receptor sites. What medications treat opioid disorder? Methadone; Buprenorphine, buprenorphine + Naloxone What medication for opioid use disorder is used with comorbid pain? Buprenorphine + Naloxone Inappropriate use of what substance may be due to uncontrolled pain? Opioids What are the Naltrexone delivery methods? Tablet; Injectable; Implant What is one form of Naltrexone delivery method limited to inpatient use? Implant What is the mechanism of action buprenorphine? Mu receptor partial agonist for opioid withdrawal What medication taken too soon after last opioid use increases the chances of intense withdrawal that comes on very quickly (precipitated withdrawal)? Buprenorphine What are symptoms of opioid intoxication? Nausea and vomiting; Respiratory depression; Constipation; Itching; Mioisis (small pupil); Euphoria; and Sedation What withdrawal symptoms of opioids? Nausea and vomiting; Diarrhea; Dehydration; Irritability; Restlessness; Yawning; Twitching; Increased heart rate and blood pressure; Chills; Increased temperature; Rhinorrhea; Lacrimation; Dilated pupils Oxazepam and lorazepam What benzodiazepines with a long half-life are used to treat AUD? Diazepam and chlordiazepoxide What benzodiazepines with a moderate half-life are used in AUD patients with liver disease? Oxazepam and lorazepam What are the treatments for alcohol withdrawal symptoms? Diazepam intravenous; Lorazepam intravenous or intramuscular; Thiamine intravenous or intramuscular; Addressing electrolyte imbalances What are the treatments for DT? Acute care management; Parenteral diazepam or lorazepam; Thiamine; Antipsychotics if necessary What is the mechanism of action of disulfiram? Via negative reinforcement, where drinking is avoided due to unpleasant effects. What is the mechanism of action of Acamprosate? NMDA receptor antagonist How is Acamprosate cleared? Renally What medication can be given to patients with AUD with hepatic dysfunction? Acamprosate What medication is suitable for AUD with comorbid OUD? Naltrexone What medication reduces consumption by decreasing reinforcement properties? Naltrexone What medication only deals with physical dependence, but does not address the psychological component of smoking? NRT What medications are oral stop-smoking aids? Varenicline; Bupropion; Clonidine "Very Bad Cancer" What are the "Very Bad Cancer" medications? Varenicline; Bupropion; Clonidine What medication for smoking cessation treatment should be observed for neuropsychiatric symptoms that include changes in behavior, hostility, agitation, depressed mood, and suicide-related events that include ideation, behavior, and attempted suicide? Bupropion What is the treatment for cocaine induced chest pain or myocardial infarction? Intravenous benzodiazepines What medications can treat agitation in patients with dementia? Atypical antipsychotics What type of medications are used only for short-term and acute episodes of aggression, agitation, and psychosis in patients with dementia? Benzodiazepines What is a reversible condition that may be caused by drugs, electrolyte imbalance, low O2 saturation, infection, reduced sensory input, intracranial events, urinary retention, or myocardial issues? Delirium What are the 4 stimulants for treating ADHD? Methylphenidate; Amphetamine salts; Dexmethylphenidate; Dextroamphetamine What are the "Man, ADHD Does Damage" medications? Methylphenidate; Amphetamine salts; Dexmethylphenidate; Dextroamphetamine What are the 5 non-stimulants for treating ADHD? TCAs; Clonidine; Guanfacine; Bupropion; Atomoxetine What are the "Calm Teens Give Better Answers" medications? TCAs; Clonidine; Guanfacine; Bupropion; Atomoxetine What baseline measurements are needed prior to starting treatment for ADHD? Height; Weight; Blood pressure; Heart rate; EKG What medication is second-line treatment, a non-stimulant, used in patients with history of SUD, or when family prefers a non-stimulant? Atomoxetine What types of stimulants are use when patient needs a duration of action longer than 4 hours, improves adherence, and is less likely to be abused? Intermediate or long acting What are common adverse effects of stimulants? Dizziness; Poor growth; Decreased appetite; Insomnia; Mood lability What are "Dizzy Patients Demand Immediate Monitoring" symptoms? Dizziness; Poor growth; Decreased appetite; Insomnia; Mood lability What symptom do children exhibit that requires blood pressure and heart rate monitoring? Dizziness If dizziness in children occurs at peak, what should the patient be switched to? A longer acting formula If a patient exhibits this stimulant associated symptom, they should be switched to a shorter acting formula? Insomnia Prior to starting a stimulant, the patient history, family history, and exam should be conducted with a focus on what? What SSRI is most likely to cause sexual dysfunction? Paroxetine What SSRI may be used to treat premature ejaculation? Paroxetine What can be done to reduce sexual side effects caused by psychotropic medications? Dose reduction What is hypogonadism? Hypoactive sexual desire in males. Life-long rather than an acquired condition. What is a Cluster B personality disorder that begins as a conduct disorder in childhood? Antisocial What is the gold-standard treatment for borderline disorder? DBT What class of medications are strongly discouraged in treating BPD due to risks of worsening impulsivity and suicidality? Benzodiazepines What type of treatment is not recommended when treating the primary traits of antisocial personality disorder? Pharmacological What is the treatment for male hypoactive sexual desire disorder and female sexual interest/arousal disorder? Hormone replacement therapy What medication is an alpha 2 agonist? Guanfacine What is the first-line medication for tic disoder? Guanfacine What are the first-line treatments options for enuresis? Desmopressin; Imipramine What is the management of IDD deficits? Behavioral therapy What stimulant medication is FDA approved for children 6+ that should not be used in patients with pre-existing cardiac conditions? Methylphenidate What FDA stimulant is approved for children 3+? Dextromethylphenidate What non-stimulant is approved for children aged 6-17? Guanfacine
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