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ANOVA and ANCOVA for Statistical Analysis of Experimental Data - Prof. Mervyn G. Marasingh, Exams of Statistics

An overview of one-way analysis of variance (anova) and analysis of covariance (ancova), two statistical methods used to analyze experimental data. Anova is used for one factor experiments with unequal or equal replications, while ancova is used for one factor experiments with a single covariate. Both methods involve estimating means, testing hypotheses using the f-statistic and t-statistic, and constructing confidence intervals. The document also covers contrasts, testing hypotheses for preplanned comparisons, pairwise comparisons, and multiple comparisons.

Typology: Exams

Pre 2010

Uploaded on 09/02/2009

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Download ANOVA and ANCOVA for Statistical Analysis of Experimental Data - Prof. Mervyn G. Marasingh and more Exams Statistics in PDF only on Docsity! Oneway Classification One Treatment (Factor) in a CRD; may be unequal replications yij = μ + αi︸ ︷︷ ︸ μi + ij i = 1, 2, . . . , t, j = 1, . . . , ni, ij ∼ iid N(0, σ2) equivalent to assuming yij ∼ N(μi, σ2), j = 1, . . . , ni for each treatment i. Also involves the assumption of homogeneity of variance i.e., same variance in each population. Estimation μ̂i = ȳi. = ( ∑ j yij)/ni, i = 1, . . . , t σ̂2 = s2 = ∑ i ∑ j(yij − ȳi.)2 N − t , N = ∑ i nîαp − αq = ȳp. − ȳq., p = q SE(ȳp. − ȳq.) = sd = s √ 1 np + 1 nq A (1 − α)100% C.I. for αp − αq (or μp − μq.) is (ȳp. − ȳq.) ± tα/2(ν) · sd where tα/2(ν) = upper α/2 percentage point of the t-distribution with ν d.f. ν = N − t Testing Hypotheses AoV Table SV d.f. SS MS F p-value Trt t − 1 MSTrt Fc = MSTrt/MSE Pr(F > Fc) Error N − t MSE(= s2) Total N − 1 The F-statistic tests H0 : μ1 = μ2 = · · ·μt vs. Ha : at least one ineq. or equivalently H0 : α1 = α2 = · · · = αt vs. Ha : at least one ineq. Testing H0 : μp = μq vs. Ha : μp = μq or equivalently H0 : αp = αq vs. Ha : αp = αq Use the t-statistic tc = |ȳp. − ȳq.| sd Rej. H0 iff tc > tα/2(ν) ν = N − t Contrasts (or Comparisons)∑ i ciμi is said to be a contrast of means μ1, μ2, . . . , μt if c1, c2, . . . , ct are constants such that ∑ i ci = 0. Examples μ1 − μ2, 2μ1 − μ2 − μ3, μ1 − 1 3 μ2 − 1 3 μ4 − 1 3 μ5 Test for Preplanned Comparisons (Equal Sample Size Case i.e., n1 = n2 = · · · = n) H0 : ∑ i ciμi = 0 vs. Ha : ∑ i ciμi = 0 tc = |∑i ciȳi.| s( ∑ c2i n ) 1 2 Rej. H0 : if tc > tα/2(N − t) or Fc = n( ∑ ciȳi.) 2/( ∑ c2i ) s2 Rej. H0 : if Fc > Fa(1, N − t) Pairwise Comparison of Means Individual Comparisons: * By the t-test of H0 : μp = μq * By the C.I.’s for μp − μq * Equivalently, using the Least Significance Difference (LSD) when sample sizes are equal. t-test for H0 : μp − μq = 0 gives Rej: H0 if |ȳp. − ȳq.| > tα/2(N − t) · s · √ 2/n︸ ︷︷ ︸ LSDα , n = sample size Multiple Comparisons: * Tukey’s procedure for all possible pairwise comparisons simultaneously (HSD). * Scheffe’s procedure for several comparisons (contrasts of the type ∑ ciμi) simultaneously. Oneway Analysis of Covariance One factor experiment in a CRD; a single covariate is also measured. Assume equal replication. yij = μ + τi + β(xij − x̄..) + ij i = 1, . . . , tj = 1, . . . , n ij ∼ iidN(0, σ 2) ⇐⇒ Assuming straight line regressions for each treatment with the same slope β Treatment 1: y1j = α1 + βx1j + 1j , j = 1, . . . , n Treatment 2: y2j = α2 + βx2j + 2j , j = 1, . . . , n ... ... Treatment t: ytj = αt + βxtj + tj , j = 1, . . . , n where αi = μ + τi − x̄.. Estimation μ̂i = ȳi.(Adj.) = ȳi − b(x̄i. − x̄..) ‘Adjusted Treatment Means’ b = Exy Exx Exy = ∑ i ∑ j(xij − x̄i.)(yij − ȳi.) Exx = ∑ i ∑ j(xij − x̄i.)2 ȳi. = ∑ j yij n x̄i. = ∑ j xij n x̄.. = ∑ i ∑ j xij nt σ̂2 = s2 MS Error from the ‘Adjusted AoV’ A (1 − α) 100% C.I. for μp − μq is (ȳp.(Adj.) − ȳq.(Adj.)) ± tα/2(ν)sd where sd = s { 2 n + (x̄p. − x̄q.) Exx 2}1/2 and ν = t(n − 1) − 1 Testing Hypotheses An analysis of covariance table SV df SS MS F Trt t − 1 SSTrt MSTrt MSTrt/MSEUnadj. Error(Unadj.) t(n − 1) SSEUnadj. MSEUnadj. Regression 1 SSReg MSReg MSReg/MSE Error(Adj.) t(n − 1) − 1 SSE MSE(= s2) Total tn − 1 SSTot Trt(Adj.) t − 1 SSTrt MSTrt MSTrt/MSE Error(Adj.) t(n − 1) − 1 SSE MSE(= s2) The F -statistic for Trt tests the hypothesis H0 : μ1 = μ2 = · · · = μt versus Ha : at least one inequality when the covariate is not present in the model. The F -statistic for Regression tests the hypothesis H0 : β = 0 versus Ha : β = 0 The F -statistic for Trt(Adj.) tests the hypothesis H0 : τ1 = τ2 = · · · = τt versus Ha : at least one inequality when β is not zero. This test is equivalent to comparing the intercepts of the regression lines i.e., H0 : α1 = α2 = · · · = αt versus Ha : at least one inequality If this hypothesis is rejected, then at least one pair of treatment effects (equiv- alently, adjusted treatment means) is different.
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