Oncologie-Cancer mamar, Summaries of Oncology

Download Oncologie-Cancer mamar and more Summaries Oncology in PDF only on Docsity! Cancerul mamar -mai present la fenci> no am - incidenta in crester la fewei tivers Factori de ris : -varsta (740 ap wasfrecent)amilial ep2 BRCAI si BRCA2↳ istoria I : 9 ILabele apar cand exista a predispositiehe dasw woleran,nedanarian) , sativa Ki67) marker 'aleravilcelular) eiproliy , prof na p53I ed (prog · veg . en evolute repla of 9saval & - APF : seriondo I genitala activa In produceits, muliparitates , I copilmai tanzi de 30du ali zafi se , obesitate ,hiper-f unibanigIwiseFrieta estagsi stil de viato : dista doyate inIgrasimi , cousurul Ide Sauturi alcodice o&I crestera poederal dupa surNapanza I Contractive rale↓ Trauma eronica: spess-ul crovic I Traumatise locale mini If repetate profesionate) Metastaze prevente : Usoase , hepatice ,pulm[ man ear : cerebraly , extarate , peritoneale , modera hematogene nostic elivic;· Diag - our HumoralaI ↑ L I modit walre san James sanules ↑ I modif·espectulufumeutule cars apar la drivazeuragrestria · Examer Clinic : - in cazul prezenti four . Hew . 1 descriv : - wewat I localizar I dimensive I consistenta L limite & I mobilitate pe planetprofundI sapoctul e Heg · supraviacent - modif care se coceleaza en extentia la distanta! · Disgu . Paraclinic : - manografia :postmenopanzae rea masutila - reografia marraral : la fenci in perivadagenitalaactiva - RMN : Merivat avografie, fol . la persisteric oila - PET-CT · Diagu. de certitudiur ,source-biopdiw - mici)-EP . exe, 2 . Zona de transitio : S 3.Bal To MoM/I SA : To Ni No /T Ne Mo - 12,3 SB : In N. Mo /Ta Ne Mo 4. Boat metastatica : "Sic : oriceT Ny Mo S : oiceT Rice N M , · Tratamenti ↑ Interventia chirurgicala' : -- 1 . Conservator (sectrectomi) : sentr tumor de dim . mici la soni navi Cdoar /v boala localizato); Ilse va T se adjuvantasca radiatera , 2. "Radicala" Castectoruis) : ↑ I . Radioterapie : -se sak face adjurant, record want soupoliaticI safpolos radiatigameso partica everg↓ Adjuvant : se face post retractorie i post mastectonicin Sala local avousato 2 . Mersdjivanta : sentr missarara tumovilor preoperator 3 . Paliativ : in bobla metastatica : metastase aspase san cerbrale. Radioterapia se prote asocia Deu chimerapa i oilo it . Chimioterapia : ~ 1 . HER2O : Ac-Decetaxel/AC-Paditaxel . AC = artecicina ciclofosfamida ↳Doxrubicina Ise face evrsult cardideic pet . e are toxicitate cardiacal 9 ! Cirlofostamida porte da cistita herragica & Paclitaxell este mai entive ematizant , das da afectare11ica swit excdGewahdag en veutoy febrilo, Neuropatieperiy I & to er1 lactic , an& latsi reactio de hipersensibilita OC awaf ⑳O A I administrata I en sustivere ico - 19 impresal & GematologC-csT nowlocyte colony stimulating factor. 2. HERLD : [DocetaxelTastuzumabe Pertuzumab IV. Horovoterapia : -na interescata prezenta RE Si RP(in special a celes estrogenici) 1 . Ferri en status post-menopanzal : al Inhibitor de aromataza dupa 2-3and de tot . en Tamoxifen ↳ i inhibitori d aromatata ca prima livie 2. Pariente in serisda es avationa : al e↳ tall activa: se face inhibitiaurgital lovarsctouie)↳ medicamentate cre i CH-RH (GnRH = gonado dog avaloying housoue) ;sine - relat - He sat asseig atot en ink . de aromataza, Icat s u Tamoxifen . I · Inhibitor de Aromataza (Anashozol, Lekoza) : adw : - initial S - seevential : - dupo Tamoxifen 2-3am & TamoxI dupo i pu Save · Tamoxi evel este antiestrogenic : aspect similar en estogenaty reparisi blockeata / · GhRH : blockeaza tinteza avariana de estrogen I . Terapia sudecular tintita : S 1 . HERLA : anticorpi movoclonali : Trastuzumab (HerceptivFalte sii anti-Herz : Pertuzumab ,feral Lapatinis , Nerotivib -I ↳ inhibitori tirsinkinazici (intra in celularactampla ca de actea 2. BRCA1 d BRCA2 : Inhibitor PARP(poliADN-riboza) polimerata) : saparid , Talazoparid