Download Organic Metabolism - Study Guide for Exam 4 - Human Physiology | BSCI 30030 and more Study notes Physiology in PDF only on Docsity! BSCI 30030, Fall 2010 Organic Metabolism: Understand how appetite and satiety are regulated o Evidence for feeding and satiety centers in the brain o Effect of endocannabinoids, leptin, ghrelin, Orexins, adipsin o Leptin and obesity Understand how “thrifty genes” cause obesity in modern environment Understand the role of Insulin in hyperkalemia Understand the relationship between insulin and epinephrine, cortisol, glucagon Understand diabetes mellitus, its symptoms and its effects on physiology o Oral glucose tolerance test: effect on normal and diabetic individuals o Diabetic hyperosmolar syndrome Define and Distinguish: diabetes mellitus (Type I, II, & III; LADA; adrenal); gestational diabetes insipidus (see Endocrine Principles lecture); gestational diabetes mellitus effects on mother, fetus (macrosomia)/baby and later consequences in the adult Understand the events in and hormones of absorptive and postabsorptive states Understand reactive hypoglycemia ß-blockers and diabetes mellitus Growth hormone and regulation of growth; types of growth abnormalities and their cause Endocrine Principles: Understand hormone transport via carrier proteins and bioavailability o Sex hormone binding globulin (SHBG) Understand the 3 major mechanisms by which hormone secretion is regulated Understand the structure and significance of hypothalamo-hypophyseal portal circulation Understand the feedback regulation of hormone secretion in hypothalamo-hypophyseal- adrenal axis o Understand the rationale behind treating adrenogenital syndrome with cortisol o Understand the rationale behind tapering prednisone dose after chronic treatment Understand the relationship between TRH, TSH, and Thyroid hormone secretion o Goiter and hypothalmo-pituitary-thyroid axis o Thyroid storm o Sick euthyroid syndrome Understand the causes of endemic goiter, Graveʼs disease and Hashimotoʼs thyroiditis
