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Pharmacognosy: Botanical Sources, History, & Uses of Natural Products, Exams of Pharmacognosy

An overview of various botanical sources of pharmaceutically important compounds, their historical background, and their pharmacological uses. Topics include the botanical sources of digoxin (digitalis lanata and digitalis purpurea), the discovery of streptomycin by waksman, and the use of akapulko (cassia alata) as an antifungal. Other topics include the history of pharmacology, secondary metabolites, and the use of various plants for treating gout, neuralgia, and diarrhea.

Typology: Exams

2023/2024

Available from 03/24/2024

DrShirleyAurora
DrShirleyAurora 🇺🇸

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Download Pharmacognosy: Botanical Sources, History, & Uses of Natural Products and more Exams Pharmacognosy in PDF only on Docsity! Pharmacognosy Digitalis lanata - botanical source of digoxin Digitalis purpurea - botanical source of digitoxin Waksman - discovered streptomycin Babylonians - made clay models of man Asafetida - aka Devil's Dung Georg Ebers - discovered the papyrus ebers Pedanios Dioscorides - wrote the book De Materia Medica Pedanios Dioscorides - Father of Pharmacology Colchicine - Tx of acute gout Allopurinol - Tx of chronic gout Ergotamine - Constituent of ergot that is used to treat migraines Ergonovine - Constituent of ergot responsible for its oxitoxic effects Opium - Stone of Immortality Tocolytic - Agents that are used to prevent uterine contraction Claudius Galen - Father of pharmaceutical compounding Galenicals - Pharmaceutical preparations with plant or animal constituents Cold Cream - aka Galen's cerate C.A Seydler - Coined the therm 'Pharmacognosy' J.A. Schmidt - aka Alligator pear Persea americana - SN: avocado Neuralgia - Avocado is indicated for what condition? seeds - What part of the avocado is used in the treatment of neuralgia? leaves - What part of akapulko is used for antifungal properties? Musa paradisiaca - SN: Banana Allisine - Active constituent of garlic responsible for its use in the management of HTN Leaves - Which part of bayabas is used as an antiseptic? Antiseptic - Pharmacologic use of the leaves of Bayabas (guava) Entada phaseoloides - SN: Gugo Gossypium hirsutum - SN: Cotton Citrus microcarpa - SN: Kalamansi Averrhoa bilimbi - SN: Kamias oxalic acid - Chemical responsible for the bleaching properties of kamias Mucolytic - Pharmaceutical use of Lagundi Citrus sinensis - SN: Chinese orange Sesamum indicum - SN: Linga (sesame) Zea mays - SN: Mais (corn) cystitis - Corn is used in the treatment of what condition? Cocus nucifera - SN: Niyog (coconut) Lauric (50%), Myristic (20%) - Chemical constituents of coconut oil (2) Lauric acid - Chemical constituent of coconut oil responsible for its antiseptic and anticancer properties Quisqualis indica - SN: Niyog-niyogan Citrus aurantium - SN: orange Solanum tuberosum - SN: Potato (patatas) Ananas comosus - SN: Pinya Bromelain - Enzyme found in pineapple Blumea balsamifera - SN: Sambong diuretic - Pharmacological use of Sambong Solanum melongena - Pelletier, Caventou - Isolated quinine (2) Pierre Robiquet - Isolated codeine Friedrich Serturner - Isolated morphine Crude drugs - Drugs that are collected and dried Crude extract - Mixture of constituents isolated from crude drugs Collection->Harvesting->Drying->Garbling - Steps in the preparation of crude extracts MgO - Chemical used to remove the bitter taste of Cascara sagrada (Sacred Bark) Garbling - Final step in the preparation of crude drugs Expose drug to 65°C, Fumigation with methylbromide, Add a drop of chloroform or carbon tetrachloride - Methods of storage of crude drugs to prevent insect attacks Hexane - Menstruum used to extract fats Ethanol - Menstruum used to extract resins Acetone - Menstruum used to extract chlorophyll Acetic acid - Menstruum used to extract Solanine Hot benzene - Menstruum used to extract chrysarobin protopectin - Constituent present in unripe fruits pectin - Constituent present in just ripe fruits peptic acid - Constituent present in over ripe fruits Pigeon - Animal used in the bioassay of digoxin Cat - Animal used in the bioassay of atropine Female chicken - Animal used in the bioassay of oxytocin Sheep (blood) - Animal used in the bioassay of heparin Rat - Animal used in the bioassay of cod liver oil Rabbit/Mice - Animal used in the bioassay of tubocurarine Dogs - Animal used in the bioassay of parathyroid hormones Chemical evaluation - Best method to determine official potency Dextrorotatory - Optical rotation of natural camphor Racemic - Optical rotation of synthetic camphor Brassicaceae - Mustard family Rutacieae -
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