BSC 680 Biotech Start-up Product Design: Project Presentation Guidelines, Study Guides, Projects, Research of Biology

Download BSC 680 Biotech Start-up Product Design: Project Presentation Guidelines and more Study Guides, Projects, Research Biology in PDF only on Docsity! BSC 680 PROJECT PRESENTATION GUIDE LINES Have you ever dreamed of being a young hot-shot entrepreneur, saving human lives, developing a new, life-saving drug, adding a useful product to the world, finding a cure for a disease, and/or becoming a multi-millionaire before the age of thirty? Well, here's your chance... Goal: Design a product for MU Biotech, a rising Biotech Start-up conveniently located in beautiful, hip, downtown Huntington, WV. The product must be new, creative, and scientifically sound! Presentation and Paper: On an assigned date, you will give a 15 minute presentation to the class on your project. Powerpoint is probably the best way to make a creative, professional looking presentation! Think of the audience as a bunch of rich venture capitalists - how will you persuade us to give up some serious cash to fund your idea? The paper should not be written in the form of a scientific research paper, but should describe the project and the methods that will be "used" (see following page). Use pictures and graphics to make your product appealing to potential investors. How do we come up with an idea? Think of useful products on the market today, new life- saving drugs that could be made possible through biotechnology, diseases where 1 protein is missing, over-expressed, or faulty, new foods or products you would like to buy yourself!! I would prefer that the product be relevant to medicine or agriculture and meet a true 'need'! (There are lots of people in need of good medicines in this world, and why shouldn't YOU be the one who provides that lifesaving drug?) In addition, it should be a 'biotech' approach - making a product using molecular biology, involving living cells, etc. Think about the scientific process - look at something, and ask questions about it! Be sure to touch base with me before or after class to talk over your ideas before you plunge in! Hey, I have a life, you know~! I understand. This project will take both time and effort, but the steps involved (problem solving, development of a new idea) are both an essential part of learning how Biotech works and an essential part of being a scientist. As an M.D. or Ph.D., you may someday want to do more for your patients that provide the current standard of care you may be involved in a clinical research trial to test a new drug - or be the one developing new ways to treat a disease! Here are some ideas:  Black roses - adding melanin genes to roses - for a sophisticated black-tie social event  Male birth control - nasal spray formulation of the human FSH receptor.  Decaffeinated coffee or low-nicotine tobacco anti-sense technology: now real products!  Transgenic pets for allergy-prone owners, with the major allergens 'knocked out' by homologous recombination (developed a few years later into an actual product - an allergen-free kitty! - by a company in England!)  ProstaSavr - for treatment of prostate cancer (and its companion product..:)  Noassitol - for treatment of obesity. (Say it out loud a few times). CEO: Dr. Hugh Jass....  Pri-Off - antisense technology for Prion disease  Invivulin: Human insulin made in the body by bacteria (a drug delivery classic...)  No Baldness, alcohol detox, or grey hair! No, nyet, nicht, non...KEEP TRYING.  No GFP anything. This means pumpkins, grass, jeans, human organs (don't ask), christmas trees, fish, or anything alive that might possibly ever, ever glow. I mean it. Your presentation will be evaluated and graded on 3 basic criteria:  1. Innovation (a new and creative bio-technological approach - not just a repeat of someone else's idea with a new gene stuck in)  2. Scientific and Technical Relevance (within reason)- must fit our current understanding and limitations of science. One free "Technological Leap of Faith" may be used per project...!  3. Significant Market Opportunity (why is there a need for this product? If it is too expensive or will be used to replace a product that is already cheap and trouble-free, than no one will invest in it!) The presentation should be very VISUAL - show as many figures and graphs as you can while explaining the details in words. Don't just read words from the slides. Each member of the audience will have an index card with rating scales for the various aspects of your presentation (see scoring sheet). (1 = poor, 2 = fair, 3 =good, 4 = excellent, 5 = outstanding).  Presentation style (disorganized? messy? professional? entertaining?)  Use of visual aids (hi-tech not necessary, but good visuals are a must for a presentation!)  Explanation of technology used (not a re-hash of the paper - but informative)  Scientific feasibility of product (is it a good idea? would it work?)  Commercial relevance of product (does it meet a need?)  Chances of buying this product (personal opinion) o Medline or PubMed is a great place to find the info you need. o It is expected that you will find, read, and incorporate info from at least 3-4 primary research papers into your team paper o Websites alone are NOT sufficient for scientific background info!  Evaluation of your product - how will you test to see you made the product correctly??? o This is a VERY important step o What will you do to test your product in pre-clinical trials? (or pre-market?) o Who will be recruited for Phase I, II, and III trials, and what 'will' be the results of each trial (effects, costs) o What regulatory paperwork will you file and when?  How product will be used in the "real world" - administered to patients, applied to crop field, etc o Oral doses once / day? Weekly injections? One time treatment? o How will the product be marketed to consumers, etc.  Costs to create product o Include costs of clinical trials or EPA testing - projections OK! o Assume you have a place to work with standard molecular biology lab facilities!  Estimated product profits and revenues o How much per treatment? o How many people will benefit from the product? o What is the cost of competing products? o What will be your annual or quarterly revenue? 5. Legal Department: Fill out and sign an Invention Disclosure Form.  The purpose of this form in real life is to record as a legal document what was invented, and when.  The Invention Disclosure Form is the first step that could potentially lead to commercialization of your technology! This document provides the basis for patentability and the data for drafting a patent application! 6. Conclusion: (~1 page)  Review and discuss your product's advantages  What "bottom line" do you want to get across to investors to get them to buy this product? 7. References Cited (1 - 2 pages)  List the references in the test as (Smith 1999).  List source of all images where they appear in the text  List references in References Cited as: o Smith JM (1999) Title, Journal, vol:pages o Smith JM (2003) "Title", in Book, pages, Publisher, City  Web site URLs are OK, but must be cited with the author and date if known, 8. Powerpoint presentation slides (6 slide per page format). Include in paper handed in on presentation day.