Replication, Transcription and Translation - Lecture Slides | CHEM 332, Study notes of Inorganic Chemistry

Download Replication, Transcription and Translation - Lecture Slides | CHEM 332 and more Study notes Inorganic Chemistry in PDF only on Docsity! 1 3 Bioinorganic Chemistry CHEM-332 Replication, Transcription and Translation DNA Transcription and Translation • DNA to DNA Replication • DNA to RNA Transcription. • RNA to Protein Translation •Both DNA & RNA are formed from NUCLEOTIDES and are called NUCLEIC acids. •Proteins are formed of AMINO ACIDS Transcri ption Translat ion DNA Transcription 1 3 RNA Transcription In the nucleus, DNA guides the synthesis of mRNA | RNA Polymerase s During transcription, RNA polymerase moves along the DNA template in the 3’-5’direction to synthesize the corresponding mRNA. =» The mRNA is released at the termination point. ANA polymerase Tenetahs, Gasca, gure, ow Bealgow Caer, Capyag Peels bomen in, pubbEAiY oo Rance Commiege mRNA leaves nucleus and goes to ribosomes U G C A U A G C G C A U A new complementary RNA strand is made (rRNA) A C G U A U C G C G U A Transcription... DNA Molecule Unravelled - One Strand is a Template for Synthesis of mRNA i » Complementary mRNA ‘ne Three types of RNA mRNA • “messenger” RNA • Carries code for proteins from DNA • Carries “codon” tRNA • “transfer” RNA • Attaches specific Amino Acids to the protein chain by matching the mRNA codon with the anticodon. rRNA • “ribosomal” RNA • Where protein synthesis takes place. protein Codons One codon codes for one amino acid. The sequence of amino acids gives rise to a protein. EX: ACG = amino acid (threonine) CGC = amino acid (arginine) GGA = amino acid (glycine) ACG GGA GGC CCA AAC CCG GCCCGC Threonine Arginine Glycine Glycine Proline Asparagine Proline Alanine Amino Acid protein DNA Replication and Protein Synthesis Comparison = Pr Orn ee Hucleus 1 3 Bioinorganic Chemistry CHEM-332 Replication, Transcription and Translation