Thermodynamics and Proteins: Important Equations and Protein Structures - Prof. Douglas A., Study notes of Biochemistry

Download Thermodynamics and Proteins: Important Equations and Protein Structures - Prof. Douglas A. and more Study notes Biochemistry in PDF only on Docsity! 9/4/2014 1 Introduction to Proteins and Amino Acids Ch. 3, pp. 75 - 81; 85 - 89 Problems: Ch. 3, p. 110, #1,6,8 BCHM 461 Sept. 4, 2014 Review of Bioenergetics and Thermodynamics Ch. 1, pp. 20 - 29 Ch. 13 pp. 506 - 511 Problems: Ch. 13, p. 538, # (1), 2-5, 6, 8, 14 If your name appears on this list, please report to the Undergraduate Programs Office, room CHEM 1206, after class. Jorge Acuna Avital Gewirtz Jennifer Hamilton Cecelia Kampsen Ana Reveron 9/4/2014 2 Thermodynamics - The 4 important equations Important equation #1: G = H – TS #2: G = G°' + RT ln(Q) #3: G°' = – RT ln(Keq) #4: G = (maximum work) Thermodynamics - The 4 important equations Important equation #1: G = H – TS Enthalpy (H) - energy (heat) released when bonds form; energy (heat) absorbed when bonds break. Entropy (S) - amount of order/disorder. Examples (see also Box 1-3, pp. 22 - 23): low entropy high entropy rigid molecule flexible molecule (few conformations) (many conformations) immobile / slow motion mobile / rapid motion concentrated solution dilute solution few, large molecules many, small molecules 9/4/2014 5 (Some of) The Amino Acids in Proteins Table 3-1, p. 77 Memorize: Names, 3-letter abbreviations, 1-letter symbols approximate pKa’s Be able to draw complete structures (see Fig. 3-5, p. 79), with correct stereochemistry (L-configuration) Fig. 3-6, p. 80 9/4/2014 6 The 20 Amino Acids in Proteins From Fig. 3-5, p. 79