Weekly Lecture Schedule for CHEM 14B: Stereochem. & Electron Delocalization - Prof. L. Lav, Study notes of Chemistry

Download Weekly Lecture Schedule for CHEM 14B: Stereochem. & Electron Delocalization - Prof. L. Lav and more Study notes Chemistry in PDF only on Docsity! Weekly Lecture Schedule CHEM 14B Instructor: Dr. Laurence Lavelle SPRING 2004 WEEKS 9 & 10 Stereochemistry & Electron Delocalization and Resonance Read: Bruice Ch 5.1 to end of 5.11 Problems: 1, 2, 4, 5, 7, 8, 10, 11, 14, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33 Read: Bruice Ch 7.1 to end of 7.9 Problems: 4, 5, 6, 7, 8, 9 After going through the readings & problems and attending the lectures & discussion groups, you should be able to: • Identify and give examples of constitutional isomers, enantiomers, diastereomers and meso-compounds. • Know which isomers (constitutional, enantiomers, diastereomers) have the same or different chemical and physical properties. • Understand that enantiomers rotate the plane of plane-polarized light in equal but opposite directions. • Understand the terms d-isomer, l-isomer and racemic mixture. • Know how to determine if a molecule is chiral. • Determine if a compound is optically active. • Understand the terms plane of symmetry, center of symmetry and stereocenter, and identify them in molecules. • Give examples of chiral biological molecules and know why chirality is important in biological systems and drug development. • Know and apply the R,S naming of enantiomers. • Draw and interpret Fischer projections. • Be able to convert 3-D representations to 2-D Fischer projections and the reverse. • Use Fischer projections to test for superposability. • Determine the number of stereoisomers for linear and cyclic molecules with more than one stereocenter and draw their 3-D representations. • Be able to identify a carbohydrate (aldose & ketose) by its 3-D representation or by its Fischer projection or by its general formula.