Synopsis: Chirality Goals and Assignments - Fall 2001 | CHEM 30A, Lab Reports of Organic Chemistry

Download Synopsis: Chirality Goals and Assignments - Fall 2001 | CHEM 30A and more Lab Reports Organic Chemistry in PDF only on Docsity! Chem 30A, Fall 2001 Prof. Garrell Week 4/5a Synopsis: Chirality Goals and Assignments for Oct. 26 through Oct. 31 TOPICS: • Introduction to symmetry • Chirality • Representing stereoisomers: R,S notation; Fischer projections • Cis,trans isomerism of cycloalkanes • Optical activity • Optical purity, enantiomeric excess GOALS: • Be able to identify and distinguish constitutional isomers, conformers, and stereoisomers (enantiomers, diastereomers) • Be able to identify planes of symmetry and centers of symmetry in simple molecules, and to identify meso compounds • Be able to identify stereocenters and assign R,S configuration • Be able to convert between perspective views and Newman and Fischer projections • Understand why the physical properties of stereoisomers may be similar or different • Understand “optical activity” and its significance in the laboratory • Be able to use polarimetry data to determine optical purity and enantiomeric excess. ASSIGNMENTS: Readings: Brown & Foote §3.2–3.9; 25.1 PROBLEMS Brown & Foote: Ch. 3: #12, 13, 15-18 (carried over from Wk. 3 synopsis); 19, 21, 22, 25- 27, 29, 30, 33, 34, 35, 36. Be sure to do all the in-text problems, including 3.8 & 3.9. Optional, but strongly suggested: Vining CD: Supporting Concepts module on Stereochemistry. Hardinger practice problems & tutorials: Stereochemistry (http://web.chem.ucla.edu/~harding/cfqpp/stereo/stereo.html), and links to tutorials on Identifying Sterocenters, Determining Molecular Chirality, Classification of Isomers, Stereocenter Nomenclature (R/S System), Drawing Enantiomers and Diastereomers, Specific Rotation and Related Calculations. UPCOMING DATES & DEADLINES: MIDTERM #1 regrade requests: Follow procedure described in the Chem 30A Course Description. Submit only to Prof. Garrell, no later than 10 AM Wednesday, October 31. Week 5 quiz: Topics from B&F 3.1–3.3, and conformations of cyclic alkanes revisited (redemption points).