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Cell Membrane Transport and Osmosis - Prof. Douglas N. Ishii, Study notes of Biology

An overview of the processes of transport across the cell membrane, including primary and secondary active transport, uphill and downhill transport, and osmosis. It covers the role of transporters such as na+/k+ atpase and ca2+ atpase, and discusses the concepts of isotonic, hypertonic, and hypotonic solutions. The document also introduces the processes of endocytosis and exocytosis.

Typology: Study notes

2011/2012

Uploaded on 01/20/2012

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Download Cell Membrane Transport and Osmosis - Prof. Douglas N. Ishii and more Study notes Biology in PDF only on Docsity! 20 January Na+ concentration higher outside the cell Ca2+ Cl- HCO3 - Glucose K+ concentration higher inside the cell Mg2+ Pi Amino acids ATP Protein Four Primary Transporters Na+/K+ ATPase 3 Na+ out 2 K+ in H+/K+ ATPase 1 H+ out 1 K+ in Ca2+ ATPase Ca2+ out H+ ATPase H+ out They use 1/3 cellular ATP Uphill transport Secondary Active Transport Cotransport Primary transporter (e.g. Na+/K+ ATPase) Second transporter is coupled to primary (e.g. pump Na+ in (downhill) while moving another molecule uphill) Energy of Na+ leaking back into the cell used to move other molecule In countertransport, a molecule is pulled out of the cell while another is moved downhill into the cell (or vice versa) Two molecules involved in countertransport move in opposite directions Pure water โ€“ 55.5 M Solute โ€“ 1 M glucose, 1 Osm โ†’ 54.5 M H2O 1 M NaCl, 2 Osm โ†’ 53.5 M H2O 1 M MgCl2, 3 Osm โ†’ 52.5 M H2O Osmolar shows moles of solute โ€“ 1 M NaCl โ†’ 1 M Na+, 1 M Cl- = 2 M High osmolarity, lower water concentration V1C1 = V2C2 Isotonic โ€“ same concentration of nonpenetrating solutes on either side of membrane Greater solute concentration outside โ€“ hypertonic โ€“ cell shrinks Lower solute concentration outside โ€“ hypotonic โ€“ cell swells
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