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The Steps of Muscles contration: the sliding Filament theory, Slides of Health, psychology

Muscles Contraction Theory in explain different steps like 1. ATP hydrolysis by myosin, step 2. Myosin attaches to actin, step 3. The Power Stroke and step 4. detachment of Myosin.

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2021/2022

Uploaded on 03/31/2022

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Download The Steps of Muscles contration: the sliding Filament theory and more Slides Health, psychology in PDF only on Docsity! he Steps of Muscle intraction: The Sliding aC mle) Yr A Key events that must take place before the contraction of a muscle fiber begins: • SR releases calcium ions into the cytosol • The calcium ions will bind to troponin which causes the troponin-tropomyosin complexes to move away from the myosin binding sites on actin. • Once this happens contraction can begin. • The process is similar to rowing, each myosin head rows forward using the actin as a base to pull from. Step 3: The Powerstroke • Phosphate release by myosin triggers the actual power contraction stroke • ADP pocket opens up on the myosin head • Myosin head rotates and releases the ADP • As the head rotates it moves in a ratchet like motion and pulls the thin filaments closer to the center of the M line of the sarcomere Step 4: Detachment of Myosin • When the ratchet motion is over the myosin awaits another ATP so it can be released from the actin binding site • If an ATP is available the myosin detaches and begins another stroke of the cycle • If not the Myosin remains locked in place and the muscle remains locked up as well this is called “rigor-mortis” Summary Points • Calcium ions are needed to start the cycle • The movement of myosin and actin is like rowers moving across water • Myosin heads will keep binding with actin sites until the ATP runs out or the Calcium levels decrease
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